Can NadPrep RNA & DNA Library Co-Preparation Module be compatible with EDTA-eluted samples?

This module can tolerate nucleic acid samples containing 6 μL of EDTA (1 mM), resulting in a final concentration of 0.3 mM in the cDNA first-strand synthesis system. At this concentration, RNA reverse transcription inhibition is minimal, and the efficiency of enzymatic digestion is unaffected. Before library preparation, confirm the sample solvent. If it exceeds the recommended EDTA threshold, it is necessary to purify nucleic acid samples using 2X NadPrep SP Beads, replacing the elution reagent with Nuclease Free Water before proceeding with library preparation.