Is NadPrep ES Hybrid Capture Reagents v2 compatible with the bead-based concentration method?

NadPrep ES Hybrid Capture Reagents v2 is compatible with the bead-based concentration (BC) method. Compared with the vacuum concentration (VC) method, BC method is simpler to operate, faster, and more suitable for automated platforms (see the Appendix of the user manual for details). It should be noted that due to differences in purification recovery efficiency, the captured library yield may be slightly lower when using BC method compared with VC method.