Exhibition Preview | Nanodigmbio Invites You to Join Us at Hospitalar 2025, Brazil International Medical Device Exhibition in São Paulo

01 Hospitalar Overview

2025 Brazil International Medical Device Exhibition (Hospitalar) will take place from May 20 to 23 at the São Paulo Expo. As one of South America’s largest healthcare industry exhibitions, Hospitalar is designed to offer professionals an efficient platform for business matchmaking, industry networking, and knowledge exchange. This year’s event is expected to bring together over 1,200 exhibitors and brands from more than 80 countries and regions, attracting upwards of 80,000 industry visitors to showcase the seamless integration of cutting‑edge technology and advanced medical equipment. Concurrent forums and interactive sessions will build open bridges between attendees and industry leaders, facilitating discussions on emerging trends, fostering international collaboration, and driving innovation and advancement in Latin America’s healthcare sector.

2.1 Conference Information

Dates: May 20-23, 2025

Venue: São Paulo Expo, São Paulo, Brazil

NadAuto-series Fully Automatic End to End NGS Solution

NadAuto‑D4(R) Fully-automated NGS Workstation, independently designed and developed by Nanodigmbio, is a flexible‑throughput automation platform engineered to maximize laboratory efficiency. It supports the full NGS workflow, including sample aliquoting, nucleic acid extraction, DNA normalization, purification, quantification, sample pooling, library preparation, and hybrid capture. NadAuto‑D4(R) features four independent pipetting channels, seamlessly integrated with an optional thermal cycler, temperature control module, heating and oscillating module, purification module, fluorometer, UV lamp, and HEPA filter. With 20 SBS‑standard deck positions, it flexibly accommodates 1–16 pre-libraries preparation and 1–8 hybrid capture reactions to meet diverse throughput requirements.

In addition, Nanodigmbio offers multiple automated workstations tailored to different applications and throughput needs, all of which can be intelligently networked for enhanced multi‑instrument automation and coordination.

To better integrate with the Fully-automated NGS Workstations, Nanodigmbio has launched the plate-based packaging reagents for pre-library preparation and hybridization capture designed specifically for NadAuto-series to further shorten reagent preparation time and optimize the operating experience. This design pre-loads all reagents into standard plates, significantly reducing manual placement and pipetting operations. This not only effectively minimizes the risk of human error but also greatly enhances experimental efficiency, allowing users to perform automated operations more smoothly.

Optimized Highlights of Plate-based Packaging Reagents

• Significantly reduces reagent preparation time: Experiments can be started within 10 min.

• Shortens automation runtime: Eliminates lengthy reagent aliquoting steps, reducing operation time by 5%-8%.

• Flexible throughputs adaptability: Supports variable sample numbers to meet different throughput requirements for library preparation.

• Aluminum foil heat-sealing packaging: Ensures sealing and stability during transportation and storage.

• No concerns about reagent loss.

• Saves storage space.

NadDrop 2000+ UV-Vis Spectrophotometer

NadDrop 2000+ UV-Vis Spectrophotometer is a high-performance optical analysis instrument designed for precise and efficient quantification of nucleic acids and proteins, offering a full wavelength range of 180-840 nm. Utilizing a fiber-stretch sample pedestal, it enables high-sensitivity measurement with only 0.5 μL of sample in seconds, without the need for cuvettes or capillaries, ensuring excellent repeatability and stability. Its wide detection range significantly reduces error-prone manual dilutions, streamlining experimental workflows.

NadDrop 2000+ combines precise measurement, user-friendly operation, and minimal consumable needs, making it an essential instrument in research applications such as molecular biology, genomics, and proteomics, and an indispensable asset in any laboratory.

μCaler Multi-scenario Application Solutions

μCaler Hybrid System is a liquid-phase hybridization capture technology optimized for small-panel targeted enrichment. Together with μCaler NanoBlockers and the innovatively designed μCaler Panels, it forms a complete hybrid capture solution capable of completing the entire library preparation workflow within a single day.

μCaler Panel, developed based on Nanodigmbio’s proprietary technology, is available in both commercial and customized panels/probes. Its innovative design enables rapid probe-target binding within the reaction system, with multiple probes stabilizing the target region through cooperative hybridization.

Powered by this system, Nanodigmbio has launched two featured solutions: the μCaler DNA Full Screen System (for synchronous detection of DNA methylation and mutation) and the NGS-MRD System, supporting both tumor-informed analysis (custom panels) and tumor-uninformed analysis (μCaler AML Panel). Additional applications include hotspot mutation detection in common cancers (μCaler HotSpot Panel), pan-cancer methylation profiling (μCaler EMS Panel), and respiratory pathogen detection (μCaler RP Panel).